What is PDO?
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What is PDO?
Abbreviation of polydioxanone
Colorless crystal form, biodegradable synthetic polymer
Degradable by hydrolysis
Mainly excreted by urine
Period of biodegradation: 6-8 months
PDO is an abbreviation of polydioxanone, and is widely used as surgery stitch thread which is also safe to human body. As a colorless biodegradable synthetic polymer, it is a monofilament, so hydrolyzed in body and then naturally excreted by urine within 6 months. Thus, PDO is safe to human body. PDO procedure leads to mechanotransduction within skin by forming vector among fine threads (FT) when FT is inserted in a fixed direction. Inserted PDO operates in the cell as mechanical external stimulus, and brings about the following effects by providing external stimulus within skin.
- Production of collagen
- Circulation of microvessel
- Increase of cell metabolism
- Surrounding tissue adhesion
- Surrounding tissue anchoring
- Decrease of cellulite
- Relaxation of muscles
- Increase of lipolysis
- Inducement of skin regeneration
- Regeneration and cellular activities of skin and subcutaneous tissue
- More than 300 times increase of EGF
- More than 350 times increase of FGF
- More than 400 times increase of IGF
- More than 150 times increase of TGF-ß
- More than 1000 times increase of VEGF